Abstract

The treatment options and prognosis of recurrent head and neck squamous cell carcinoma are largely determined by site, extent of disease,and previous treatment. Salvage surgery represents the primary curative option when recurrent head and neck squamous cell carcinoma is resectable. The common factors that affect the prognosis of patients undergoing salvage surgery include surgical resection margin pathology, radiation therapy, advanced initial and recurrent tumor stage, and presence of concomitant neck disease. This paper reviewed the advancement of salvage surgery for recurrent head and neck squamous cell carcinoma.

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