Abstract
Norepinephrine (NE) elicited a saturable, concentration-dependent contraction in rat aortic strips (EC50, 9 nM). Phenoxybenzamine (PBZ) inhibited, irreversibly, the NE-induced contraction (max. inhibition at 50 nM applied for 10 min.). The protection of the α-receptor by NE showed a biphasic concentration dependence. These results are interpreted in terms of a 2-receptor model.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
