Adrenalectomies: Clinical findings, laboratory, and histological findings

Abstract

Introduction: An increasing number of patients are considered for surgical removal of adrenal tumors, including pheochromocytomas (PCC). This study evaluated the presentation and surgical outcomes of individuals with adrenal tumors including PCC.Methods: Data, including histological, radiological, and biochemical, were collected prospectively of all patients operated for adrenal tumors, via the computerized hospital information database, between 2006 and 2018. Statistical analysis was performed by STATA program, using the Student test or Kruskal–Wallis test being used for continuous variables. Chi-squared or Fisher tests were used to compare categorized variables.Results: In this study, there were 112 patients, of which 54 were males and 58 females, mean of 32 years, the minimum age of 23 days, and a maximum of 78 years. Hormonally active tumors accounted for 58.51% and inactive hormone was accounted for 41.49%. The mean (SD) of the tumor dimensions was 6.00 (3.82), 5.31 (3.16), and 5.91 (2.93) mm for length, height, and width, respectively. The mean (SD) for the duration of surgery for males was 183 (98.8) and for females was 188 (101.06) min, with a hospital stay of 9.9 (6.86) days for males and 7.11 (6.16) days for females. The most common etiology was neuroblastoma (29.5%), followed by adrenocortical adenoma (16.1%), and 7.1% were PCC.Conclusion: Our population may have a slower recovery and more complications after resection of adrenal tumors including PCC. However, most complications may be minor, surgery was equally feasible and may not result in mortality in this vulnerable group of patients. Meticulous preparation for surgery is crucial among our population and particular attention should be focused on maintaining balance between the adrenal disease and comorbidities.