Abstract
CFW and CF 1 male mice were weaned, isolated for 7 days, then randomly assigned to one of three cage sizes for an additional 7 days. There was a significant increase in adrenal weights for males of both strains after exposure to the smallest living space. A significant decrease in final body weights occurred after housing CFW males in medium size cages and CFW and CF 1 males in small cages. The possible influence of spatial parameters on the endocrine stress response of populations of high density is discussed.
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