Administration of dinoprostone suppositories in induced labor for full-term pregnant women with hypertensive disorders

Abstract

Objective To evaluate the administration of dinoprostone suppositories in induced labor for full-term pregnancy women with hypertensive disorders. Methods One hundred and nine full-term pregnant women admitted in Jiaxing Maternal and Child Health Care Hospital from February 2010 to December 2011 were included in the study. The subjects included 43 cases with pregnant hypertension (group A), 36 cases with mild preeclampsia (group B), 30 cases with severe preeclampsia (group C), and 30 full-term normal puerpera were also included (group D). Dinoprostone suppositories were placed in the vagina for induction. The cesarean delivery rate and perinatal prognosis were compared among the four groups. Results The cesarean delivery rate in group C was higher than other 3 groups; there was no significant difference among groups A, B and D. The rates of fetal distress and postpartum hemorrhage in group C were higher than those in other 3 groups; there were no significant differences in rates of fetal distress and postpartum hemorrhage among group A, B and D, while there was no difference in rate of neonatal asphyxia among all groups. Conclusion Dinoprostone is effective and safe in inducing labor for full-term pregnancy women with hypertensive disorders. Key words: Dinoprostone; Hypertension, pregnancy-induced; Labor, induction