Abstract

Pterygium recurrence is one of the most common complications in pterygium surgery. And various medicines combined with surgery could further reduce the rates of recurrence. As traditional adjunctive therapies, anti-metabolic drugs have been applied to prevent the recurrence of pterygium for decades. However, mitomycin C has been not available because of its shortage source, and 5-fluorouracil is less effective. Recently, some medicines such as anti-vascular endothelial growth factor agents, cyclosporine A and interferon, characterized by anti-proliferation and anti-angiogenesis, provide new approaches to prevent the recurrence of pterygium. However, the high costs of above medicines and uncertain long-term effects are still huge problems. (Int Rev Ophthalmol, 2018, 42: 129-133) Key words: pterygium; recurrence; drugs

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