Abstract

ABSTRACT Lesions involving adipose tissue and the thyroid gland are usually rare. In the present report, adipose metaplasia is associated with Hashimoto's thyroiditis with nodular hyperplasia and oncocytic adenoma in a 40-years-old female patient, which is one of the first reported cases of this association. The main clinical finding is the diffuse goiter, and the differential diagnosis must be performed to exclude the possibility of malignancies. The treatment is performed through total thyroidectomy. Thus, it is important the physicians be aware of this pathology with a view to a more effective clinical reasoning and to exclude more serious possibilities.

Highlights

  • Lesions involving adipose tissue and the thyroid are rare and have few cases reported in the history of Medicine[1]

  • The presence of adipose tissue has been reported in association with several pathologies, such as adenolipoma, lymphocytic thyroiditis, amyloid goiter, papillary carcinoma and liposarcoma[1]

  • The anatomopathological profile and immunohistochemical profile were consistent with adipose tissue metaplasia in the thyroid associated with Hashimoto’s thyroiditis with nodular hyperplasia of oncocytic cells and oncocytic adenoma

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Summary

Introduction

Lesions involving adipose tissue and the thyroid are rare and have few cases reported in the history of Medicine[1]. The presence of adipose tissue has been reported in association with several pathologies, such as adenolipoma (thyrolipoma), lymphocytic thyroiditis, amyloid goiter, papillary carcinoma and liposarcoma[1]. In this case report, adipose metaplasia was associated with Hashimoto’s thyroiditis with nodular hyperplasia and oncocytic adenoma. Hashimoto’s thyroiditis is an autoimmune disease that results in thyroid destruction and gradually affects its hormonal function. It is the most common cause of hypothyroidism in iodine-sufficient areas; usually reaching individuals aged 45-65 years and is more common in women than in men. Because of the unusual nature of the disease, especially associated with Hashimoto’s thyroiditis, this is the subject presented in this case report

Case description
Discussion

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