Abstract
Purpose: To identify the association if any, of inflammatory markers (IL-6 and hsCRP) with adiponectin in obese diabetic, non-obese diabetic, obese non-diabetic and healthy (control) people in North Indian population. Materials and Methods: Total 88 volunteers were distributed in 4 groups: obese diabetic, non-obese diabetic, obese non-diabetic and healthy controls. The blood chemistry parameters were analyzed and serum adiponectin, IL-6 and hsCRP levels were measured by ELISA. Result: Significant reduction was observed in serum adiponectin levels in obese and diabetic group as compared with healthy population. Similarly, significant increase was observed in IL-6 and hs CRP levels in obese and diabetic groups compared with healthy control group. Conclusion: From our data it can be summarized that there is a significant change in both adiponectin (reduction) and IL-6 and hsCRP (increase) levels in obese diabetic, non-obese diabetic and obese non-diabetic people in Indian population. The result of our study showed that adiponectin levels are reduced in obesity and type-2 diabetes, and there is a reciprocal association of hsCRP and IL-6 in the above conditions.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
