Abstract
Over a ten-year period on a private hospital service, adenomyosis was encountered in 281 cases or 8.8 per cent of the surgically removed uteri. In 71 per cent of these patients, the symptoms were due to or contributed to by the adenomyosis, yet the disease was diagnosed or mentioned preoperatively in only 23 per cent of cases. The ectopic endometrium showed functional response over all in 33 per cent of cases where this could be evaluated and secretory response to ovarian progesterone in 26.6 per cent of cases where the surface endometrium was secretory. Functionally active ectopic endometrium, however, did not always produce clinical symptoms. Sixty-seven patients had a history of treatment with synthetic progestins, and pseudodecidual change in the ectopic endometrial islands was demonstrated in some of these. The symptoms of the disease were not alleviated, and no evidence was found in this study that the widespread use of these drugs in the last decade has altered the clinical picture of adenomyosis.
Published Version
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