Abstract
ABSTRACT Adenine nucleotides (ATP, ADP and AMP) have a uniquely crucial role in the metabolism of living cells, and in the regulation of that metabolic activity. Their role might be expected to be somewhat different in eukaryotes and prokaryotes because of compartmentation of the adenylate pools in mitochondria and the cytosol of the former organisms and the extra metabolic flexibility and control this confers on the cell. However, within bacteria and in eukaryotes it is perhaps a priori reasonable to suppose that the adenine nucleotide pools would be maintained in a similar manner. In exponentially growing bacteria this appears to be the case, with relatively similar adenine nucleotide contents and ATP:ADP and ATP:AMP ratios, as shown by similar energy charge values, in a wide variety of species.
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