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Abstract
When a sample of arterial blood is analysed for oxygen tension and, using a modern oximeter, for haemoglobin concentration and saturation, it is possible to calculate the position of the oxygen dissociation curve and two new variables: "P95" and "C(a-x)O2". P95 is the tension at which the haemoglobin would be 95% saturated and can, therefore, constitute a target tension for near-maximum arterial content of oxygen. C(a-x)O2 (the "conditional extraction" of oxygen) is the amount of oxygen, in ml/dl blood, which can be extracted from the arterial blood for a hypothetical mixed-venous oxygen tension PxO2. It is explained how it is possible to estimate the adequacy of tissue oxygenation by comparing any available estimate of the required extraction (normally about 5 ml dl-1) with conditional extractions calculated for three hypothetical values of PxO2 covering the clinical range. Methods of calculation are given. For accurate results at high arterial saturations, a peripheral venous sample may be required in addition to the arterial sample.
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