Abstract

Addition of carbon radicals generated from organoselenium reagents (PhSeR: R= COPh, CO 2Et, CH 2CO 2Et, CH 2COMe, and CH 2CN) to 4′,5′-unsaturated uracilnucleosides was found to provide a highly efficient entry to CC bond formation at the 5′-position, the stereochemical outcome of which is dependent upon the hydroxyl protecting group.

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