Adaptive Regulation for Noise-Aided Weak Signal Detection inSpiking Neurons

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Spiking neurons usually change their membrane properties, especiallyion channel activity, during adaptation or synaptic modification toimprove information processing and transmission. Using simple andbiophysically realistic models, our analyses reveal thatactivity-dependent regulation of membrane properties contributes tosensitivity adaptation that improves the neuron ability of detectingsub-threshold signals in the presence of background noises. Theimprovement is achieved by regulating the conductance of ion channelson the membrane, dependent on the neuron firing activity.