Abstract

Fusarium tricinctum (Corda) Sacc. emend. Snyder and Hansen1 has been isolated from most small grains2,3 and occurs very frequently on mouldy corn in Wisconsin4. Certain strains of this fungus, isolated from mouldy corn, have been found to be extremely toxic to rats4. The toxin produced by one isolate was purified in crystalline form and appeared to be a hydroxyester or lactone, C17H24O6 (ref. 4). Subsequent investigations have indicated that this compound is 4-15-diacetoxyscirpen-3-ol, C19H26O7, which is produced by Fusarium equiseti (Corda) Sacc.5,6. Work at present being done on the structure of another toxin7, produced by a second strain of F. tricinctum, has indicated that this toxic compound is related to but not identical with diacetoxyscirpenol. Only the toxin from this second strain was used in these investigations.

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