Abstract
Superficial skin papillary capillaries with blood supply from a superficial vascular plexus and regulated by local metabolic needs supply oxygen and nutrients for epithelial cell proliferation. A deep vascular plexus regulated by autonomous nerves serves body thermoregulation. In healthy volunteers, we assessed circulatory effects of a standardized skin trauma by CAVM, DRS, and LDPM to assess the measuring depth of the three techniques and to describe the acute trauma effects on nutritive and thermoregulatory perfusion. Volunteers (n=12) were examined at baseline and after induction of a 5.0mm×1.0mm incision on the forearm; 30minutes after the trauma induction, data were collected at 0-1, 2-3 and 30mm distances. LDPM showed hyperemia at 2-3mm distance (35.8±15.2a.u.), but not at 30mm distance (7.4±2.5a.u.) compared to baseline (8.8±1.8a.u.). The DRS saturation increased at 2-3mm (71.2±4.8%), but not at 30mm (49.8±7.9%) compared to baseline (45.8±7.4%). Capillary density and flow velocities were unaffected at all distances. The results indicate that skin nutritive papillary capillary function can be assessed by CAVM and DRS, but not with LDPM because of its dependence of the deep plexus perfusion.
Published Version
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