Abstract
Background and Aims: Acute myocardial infarction (AMI) below 45 years of age constitutes a specific subset of population having different risk factors and clinical features as compared to older patients. The aim of the study was to assess the frequency and risk factors of AMI in patient's ≤45 years of age.Patients and Methods: A cross-sectional retrospective study was conducted involving 187 patients with clinical diagnosis of AMI. They were studied for risk factors, clinical characteristics, coronary angiographic finding and in-hospital outcome during January 2015 and December 2015 at Benghazi medical center, Benghazi - Libya. Results: Out of total 187 AMI patients studied, there were 41 (22%) young patient ≤45 years of age. Risk factors was studied, smoking was found in 63.4% of young patients, 44% were had history of dyslipidemia, 14% had history of alcohol drinking and 12% had family history of coronary artery disease. In young AMI patients, anterior wall STEMI was the most common site and single vessel disease was the most common finding in coronary angiography. However, 13% of patients have normal or non-obstructive coronary lesions. Arrhythmia (24%) and heart failure (17%).Conclusion: In our young AMI patients, smoking was the single most important modifiable risk factor, other conventional risk factors are less strongly associated than older patients. Our young patients tend to have less extensive coronary artery lesions. The presence of normal or non-obstructive coronary lesions would suggest possibility of different mechanism of myocardial necrosis.
Published Version
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