Abstract
Acute lymphoblastic leukemia is a malignancy associated with overproduction of immature lymphocyte population. There is a progressive replacement of bone marrow and other lymphoid organs by abnormal cells. The common symptoms include fatigue bruising spontaneous bleeding and infections. This is more common in children. A patient with leukemia is at an increased risk for infections both as a result of disease itself and due to complications associated with chemotherapy. Neutropenia is the major determinant for development of infections. Radiologic lsquoHalo signrsquo is characteristically observed in angio-invasive fungal pneumonia. Early institution of antifungal regimen based on this sign results in improved outcomes.Multiple complications are observed in leukemia such as development of vascular aneurysms hemorrhagic complications cellular infiltration and tumor cell lysis syndrome. Radiology plays an important role in the early diagnosis and guided interventions. A multidisciplinary approach results in improved outcomes.
Published Version
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