Abstract
Autochthonous hepatitis E virus (HEV) infection is an increasingly recognized zoonosis in western countries. It is often asymptomatic but may cause severe illness, particularly in immunocompromised patients or those with underlying chronic liver diseases. Even less frequently, cases of acute failure have been reported. In this article, we describe a case of an immunocompetent patient who presented with symptomatic acute HEV hepatitis and progressed to acute liver failure. The patient was transferred to another hospital for further management and transplant consideration. Unfortunately, he developed multi-organ failure thereafter and died before the transplantation became feasible. Subsequently, HEV was confirmed in archived serum by detection of HEV RNA using commercial RT-PCR. The results of this study have confirmed that HEV testing should be included in the initial evaluation of every acute liver failure regardless of travel history, risk factors or underlying chronic liver diseases. This approach might support clinical decisions and enable to use of potential antiviral therapy.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of IMAB - Annual Proceeding (Scientific Papers)
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
