Abstract
Without therapeutic impact, we conclude that routine measurement of biochemical analysis in the CSF is not indicated in children with acute leukemia. • Biochemical analysis of the cerebrospinal fluid (CSF) is routinely performed in children with acute leukemia in some centers while its clinical value remains uncertain. • Cytology is the gold standard technique for the detection of central nervous system (CNS) involvement in leukemia. • No significant correlation was found between CSF biochemical and cytological analyses and CSF biochemical analysis had no added clinical value in this study. • Our results suggest that routine CSF biochemical analysis may be omitted in this clinical context.
Published Version
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