Acute ischemic instructions due to the new coronavirus infection

Abstract

The study included 23 patients with acute intestinal ischemia. The average age of the patients was 59,9 ± 15,0 years, the male prevailed — 17 men (73.91 %) vs. 6 women (26.09 %). The diagnosis of a new coronavirus infection caused by SARS-CoV-2 was confirmed in all patients by the results of PCR tests (polymerase chain reaction). All patients underwent Computed Tomography of Pregnant Women with contrast examination, which was validated by a valuable instrumental study in patients with COVID-19 with suspected acute intestinal ischemia. It was confirmed that ischemia of the small intestine is the most prominent case in surgical detection, resection of the necrotic part of the small intestine with the formation of anastomosis was the most common surgical procedure, it was performed in 14 (60,85 %) patients, in 7 (30,45 %) patients resections of the large intestine were performed, and only 2 (8,7 %) patients underwent open thrombectomy. Histopathological examination was performed in 21 patients (91,30 %), revealed general symptoms, including necrosis, ulcer, hemorrhage in 11 patients (47,82 %), neutrophilic infiltration in 7 patients (30.4 %) and abscess in 3 patients. (13,04 %). An assessment of the dynamics of blood biomarkers in patients included in the study showed a steady increase in such indicators as D-dimer, LDH, ferritin and IL-6. Because of the high incidence of GI ischemia, clinicians should always be on the lookout for this disease in order to prevent its progression and promptly treat any complications. Elevated levels of CRP, lactate and D-dimer may determine predictive value as possible prognostic factors as they can be found in any patient with severe course of COVID-19.