Acute hepatitis and myositis associated with Erythema infectiosum by Parvovirus B19 in an adolescent

Maria Koliou,Sylvie Pavlides,Elpidoforos S Soteriades,Evaggelia Karaoli,Christina Christodoulou,Stavros Bashiardes

doi:10.1186/1471-2431-14-6

Abstract

BackgroundErythema infectiosum is the most common clinical manifestation of Parvovirus B19 infection although it has also been associated with rheumatologic diseases and various types of systemic vasculitides. Acute hepatitis and benign myositis however are rarely reported in association with Parvovirus B19 infection.Case presentationHere we report a 14-year old male, who developed acute hepatitis and benign myositis associated with erythema infectiosum following Parvovirus B19 infection.ConclusionParvovirus B19 infection has rarely been associated with acute hepatitis and exceptionally rarely with benign myositis. Parvovirus B19 should be considered in the differential diagnosis of acute non-A to E hepatitis and in the case of acute benign myositis presenting with a rash especially in children.

Highlights

Erythema infectiosum is the most common clinical manifestation of Parvovirus B19 infection it has been associated with rheumatologic diseases and various types of systemic vasculitides
Erythema infectiosum is the most common clinical manifestation of Parvovirus B19 infection transmitted mainly by respiratory droplets, which often occurs in outbreaks among school-aged children
* Correspondence: mkoliou@spidernet.com.cy 1Department of Paediatrics, Archbishop Makarios Hospital, 14 Longou Street, 2027, Strovolos Nicosia, Cyprus 2Cyprus Institute of Biomedical Sciences (CIBS), Nicosia, Cyprus Full list of author information is available at the end of the article association with benign myositis is exceptionally rare with only one case having been reported in the literature [8]

Summary

Introduction

Erythema infectiosum is the most common clinical manifestation of Parvovirus B19 infection it has been associated with rheumatologic diseases and various types of systemic vasculitides. Erythema infectiosum is the most common clinical manifestation of Parvovirus B19 infection transmitted mainly by respiratory droplets, which often occurs in outbreaks among school-aged children. * Correspondence: mkoliou@spidernet.com.cy 1Department of Paediatrics, Archbishop Makarios Hospital, 14 Longou Street, 2027, Strovolos Nicosia, Cyprus 2Cyprus Institute of Biomedical Sciences (CIBS), Nicosia, Cyprus Full list of author information is available at the end of the article association with benign myositis is exceptionally rare with only one case having been reported in the literature [8].

Results

Conclusion