Abstract

Objectives: MitraClip (MC) implantation has become a widely accepted therapeutic option in the treatment of severe mitral regurgitation (MR) in patients unsuitable for surgery. N-terminal B-type natriuretic peptide (NT-proBNP), a biomarker released in the ventricular wall reflecting excessive mechanical stress, is routinely used as a prognostic variable in the setting of heart failure therapy. We sought to evaluate the impact of acute post-procedural changes in NT-proBNP on clinical outcome after successful MC therapy.

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