Abstract
Introduction. MitraClip (MC) is a catheter-based device to treat mitral regurgitation (MR). This method uses a transseptal approach and is based on the creation of a double orifice mitral valve by suturing of the middle scallops of the mitral valve’s leaflets. Aim. The aim of the study was to assess the effectiveness of MC method in treating patients with severe MR. We analysed MR severity, patient’s clinical condition evaluated by New York Heart Association (NYHA) functional class, and the function of the left ventricle evaluated by Left Ventricle Ejection Fraction (LVEF). Methods. A retrospective single-centre study with patients hospitalised at the Department of Cardiology and Internal Medicine in Bydgoszcz. All diagnosed with severe MR and treated by performing MC procedure in the time period from August 2010 to December 2014. The following data from medical history (NYHA class) and echocardiography examinations (MR severity and LVEF) were analysed in three time points: before, right after the procedure, and after the follow-up period (four weeks since discharge). Results. The studied group consisted of 11 patients — 8 male, 3 female, aged 64.4 ( ± 10.2) years, treated with MC. All of the three analysed parameters improved relevantly as a result of the evaluated procedure. The percentage of patients classified as NYHA class III/IV presents as follows: 90% before the procedure, 55% after MC implantation (ns), and 44% after the follow-up period (p = 0.01). All patients suffered from severe-to-moderate (3+) and severe (4+) MR before the procedure. After implantation only 9% (ns) were still classified with 3+/4+ MR, and after the follow-up this percentage reached 18% (p = 0.0005). We observed relevant changes of LVEF. The average LVEF at baseline was 27.9 ± 2%, which increased to 29.6 ± 2% (ns) after the MC implantation and 34 ± 7% (p = 0.02) after the follow-up. Conclusion. MC therapy is effective in patients with severe symptomatic MR with congestive heart failure and decreased LVEF. It reduces MR severity both acutely and after the follow-up period and improves NYHA class and LVEF.
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