Abstract
Pharmacognostical standardization and toxicity profile of the methanolic leaf extract of Plectranthus amboinicus (Lour) SprengPreeja G. Pillai, P. Suresh, Gayatri Aggarwal, Gaurav Doshi, Vidhi Bhatia
Highlights
Humans have developed knowledge and optimized the use of plants for thousands of years according to their intelligence, genius, understanding of health, diseases and relationship with the environment (Bouiddouh, 2012)
In sub-acute treatment, H. madagascariensis extract caused a decrease in neutrophils, monocytes, red blood cells and platelets number
The administration of H. madagascariensis bark methanol extract by oral route at 5000 mg/kg did not result in any death; the LD50 is greater than 5000 mg/kg
Summary
Humans have developed knowledge and optimized the use of plants for thousands of years according to their intelligence, genius, understanding of health, diseases and relationship with the environment (Bouiddouh, 2012). These data are nowadays the basis of several scientific experiments which attest pharmacological properties of extracts derived from plants. Recent studies revealed side effects of the leaves extract of this plant on liver cells and lipid metabolism. The present study was designed to investigate the safety of methanol extract from stem bark of H. madagascariensis
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