Abstract

Non-melanocytic skin tumors encompass a heterogeneous group of lesions. Many of them are benign in nature, such as seborrheic keratosis, and others are malignant, such as non-melanoma skin cancer, which mainly includes keratinocyte neoplasms (basal cell and squamous cell carcinoma) and less frequent tumors such as Kaposi sarcoma and skin lymphomas, among others. Non-melanocytic skin tumors have diverse origins within the epidermis, the appendages, the dermal connective tissue, or subcutaneous tissue, as well as the structures that are found in the dermis, including nerves and blood vessels. Depending on its origin and nature—benign or malignant—they will have different clinical and dermoscopic characteristics. Therefore, knowing their clinical manifestations is essential for an early diagnosis and treatment. The diagnosis of these skin lesions will be made through a clinical examination and, in certain cases, will require histological confirmation, given that surgery is the treatment of choice for the majority of malignant tumors.

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