Abstract
Apfel’s active cavitation detector [Roy etal., J. Acoust. Soc. Am. 87, 2451–2458 (1990)] has been improved to allow quantification of microbubble activity in reconstituted human blood. One-microsecond-long 20-MHz tone bursts are scattered from microbubbles undergoing transient cavitation at the focus of a pulsed 1-MHz transducer. The host medium consists either of human red blood cells suspended in autologous plasma or platelet-rich plasma, with various concentrations of microbubble-based echocontrast agent present. The microbubble activity inferred from the backscattered tone bursts is compared to measured bioeffects (hemolysis, platelet aggregation) in order to determine the physical basis for cavitational damage of blood components. Current results as a function of system parameters will be presented. [Work supported by NSF MSS-9253777.]
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
