Abstract

Reorganization (disassembly) of the actin filaments in Ehrlich ascites tumor cells, either by hypotonic treatment in the presence of Ca 2+ or by addition of cytochalasin B, results in activation of the Na +/K +/Cl − cotransport system. However, other regulatory processes, some of which may be dependent on an intact filament system, are responsible for the activation of the Na +/K +/Cl − cotransport system after cell shrinkage.

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