Abstract
Twelve male pigmented guinea pigs underwent either a unilateral vestibular deafferentation (UVD) ( n=6) or sham operation ( n=6). Compared to the pre-operated salivary cortisol concentrations, the UVD operation resulted in a significant increase in night cortisol concentrations ( P<0.05) and a significant interaction between the night cortisol concentration and time ( P<0.05). There was no significant difference between the pre- and post-UVD morning salivary cortisol concentrations; nor between the pre- and post-sham morning or night salivary cortisol concentrations. This study suggests that the ocular–motor and postural syndrome is causing the activation of the hypothalamic–pituitary–adrenal (HPA) axis.
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