Abstract
The role of macrophage hydrogen peroxide in defence against mycobacterial infection is discussed — not because this is necessarily any more important than other macrophage products (reviews: [1, 2]) but more as a reflection of recently available information. First, we will describe an accumulation of evidence that peroxide has a role, then we will stage an enquiry into whether interferon-gamma (IFNγ) activates macrophages for peroxide release, and finally we will give an appraisal of direct peroxide toxicity as the mechanism of killing Mycobacterium tuberculosis by activated macrophages.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
