Abstract
Blebs are pressure driven spherical protrusions of the plasma membrane which form when a patch of cell membrane is detached from the cortex and expands under the influence of flowing cytosol. The stabilization of the membrane protrusion is characterized by a complete degradation of the old cortex (actin scar) and the formation of a new cortex beneath the protruded membrane, a process that takes about 20 seconds in Dictyostelium Discoideum cells. The mechanism by which the cortex is degraded at the actin scar and simultaneously reformed at the developing bleb boundary is not fully understood.
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