Acinetobacter baumannii’nin Bazı Antibiyotiklere Karşı Direnç Oranları: 2018 ve 2006 Yılları Sonuçlarının Karşılaştırılması

Abstract

Acinetobacter baumannii is a type of bacteria that causes serious hospital infections in intensive care units (ICUs) and immunocompromised patients. In this study, the one-year cumulative antibiogram results of A.baumannii strains, which are serious infection factors especially in intensive care patients, were retrospectively analyzed, at the same time, the results of sensitivity in a similar study conducted in our hospital in 2006 were compared with our results. Of the 388 isolates included in the study, 208 were isolated from male (53.6 %), 180 from female (46.4 %) patients, 87 % of the strains were from adults, 13 % from children (including newborns). 46.4 % of the factors were produced by the respiratory tract, 26.80 % from blood culture, 11.85 % from urine, 9.53 % from the wound 85 % of the samples were sent from intensive care units, 15 % from services (9.4 % internal service, 5.6 % surgical service), 6.95 % from the burn unit. The vast majority of the isolated A.baumannii strains were found to be adults. As a result of the antibiogram, the highest resistance rate to imipenem with 94.84 %; the lowest resistance rate was determined against colistin with 20 %. In the comparison of the results obtained in our hospital with the results of similar studies conducted in 2006, a significant increase in resistance was found for amikacin, ciprofloxacin, imipenem and meropenem (p<0.005), For trimethoprim / sulfamethoxazole, the resistance rate decreased (p>0.005). In this study, we showed that the resistance rates against A.baumannii strains increased over time, and the treatment options related to this are now very limited. Determining the resistance rates of common infectious agents at certain intervals by each hospital will be a guide in the effective treatment of infections that develop due to strains with limited antibiotic options.