Abstract
Acetylcholinesterase (AChE) and cholinesterase (ChE) activities were determined colorimetrically in selected visual and extravisual CNS areas of mother rats and their progeny, after 21 days of complete light deprivation from the birth of the offspring. Both age- and structure-specificity to light deprivation were demonstrated in AChE activity: a decrease was observed in the superior colliculi and lateral geniculate bodies of the progeny, whereas enzyme activities in other brain regions, including visual cortex, remained unchanged in either age group. The observed decrease in AChE activity can be directly related to visual function, and might be correlated with decreased synaptic transmission. Decreased sensory input at critical developmental periods, in its alteration of biochemical parameters, may also result in subsequent neural dysfunction.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
