Abstract
ObjectiveTo study the degree of acceptance of amniocentesis according to possible differences between patients who were considered at risk due to maternal age and those offered amniocentesis as a consequence of abnormalities detected by biochemical screening MethodsWe included all the patients referred for fetal karyotyping in a 7-year period. Patients were classified according to indications for amniocentesis: group I (maternal age) and group II (abnormal serum screening) ResultsA total of 9,227 patients were included: 4,859 because of maternal age and 4,368 because of abnormalities detected by biochemical screening; 176 women in group I (3.62%; 95% CI, 3.35%–3.89%) and 152 women in group II ( 3.48%; 95% CI, 3.32%–3.75%) refused the procedure. After a reconsideration period, 21 patients (12%) in group I and 22 patients (14%) in group II decided to accept the procedure ConclusionsThe overall uptake of amniocentesis for prenatal karyotyping in our center was 96.92% (95% CI, 96.74%-97.1%)
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