Abstract
Background Insulin resistance has been associated with the development of metabolic syndrome (MS), which is an interrelated cluster of risk factors for cardiovascular disease and type 2 diabetes (T2D). Several equations derived from the oral glucose tolerance test (OGTT) have been developed as surrogates for the euglycemic hyperinsulinemic clamp technique to estimate insulin resistance and insulin sensitivity.
Highlights
Insulin resistance has been associated with the development of metabolic syndrome (MS), which is an interrelated cluster of risk factors for cardiovascular disease and type 2 diabetes (T2D)
IRI was estimated by fasting insulin, fasting insulin/fasting glucose and 2h-insulin/2h-glucose ratios, FIRI, HOMA-AD, HOMA-IR, HOMA-2-IR and by the reciprocal of adiponectin, Avignon, Bennet, Gutt, HOMA2-IS, ISi, ISi 2h, Matsuda, McAuley, QUICKI, Raynaud, Stumvoll and OGIS indices
FIRI, HOMA-AD, HOMA-IR and the reciprocal of Avignon, Bennet, insulin sensitivity (ISI), OGIS and QUICKI indices were directly related with fasting and 2h-plasma glucose, glycosylated hemoglobin, triglycerides levels, systolic and diastolic blood pressure (BP), waist circumference and body mass index, but they were inversely related with HDL-cholesterol
Summary
To determine the accuracy of insulin resistance (IRI) and the reciprocal of insulin sensitivity (ISI) indices to identify MS
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
