Accuracy and Safety in Screw Placement in the High Cervical Spine: Retrospective Analysis of O-arm-based Navigation-assisted C1 Lateral Mass and C2 Pedicle Screws.

Abstract

This study was a retrospective analysis. The purpose of present study was to evaluate accuracy, efficiency, and safety of intraoperative O-arm-based navigation system for the placement of C1 lateral mass screw (C1LMS) and C2 pedicle screws (C2PSs) in high cervical spine operations. High screw misplacement rates, various pedicle morphometry and vertebral body size variations have led to a search of image-guided systems to improve the surgical accuracy of screw insertion in high cervical spine. The use of O-arm has been proposed for more accurate and efficient spinal instrumentation. Between June 2009 and August 2016, a total of 48 patients with atlantoaxial instability were surgically treated using the image-guidance system. To reconstruct atlantoaxial instability, we have been using Harm's technique of C1LMS and C2PS fixations. A frameless, stereotactic O-arm-based image-guidance system was used for correct screw placement. Postoperative computed tomographic scan with multiplanar reconstructions were used to determine the accuracy of the screw placement. A total of 182 screws, including 90 C1LMS and 92 C2PSs were inserted using image-guidance system. In total, 4.4% (4/90) of C1LMS and 7.6% (10/92) of C2PS had cortex violation over 2 mm and considered as "significant." Among the significant cortex violations, "unexpected breech" was 3.3% of all the screws inserted. Two (2.1%) screws inserted had perforated the vertebral artery canal and iatrogenic vertebral artery stenosis was proved with postoperative computed tomography angiography. When divided into time periods, 60% of significant breech occurred during the beginning stage, 40% during adaptation stage and none during expert stage. In this study, the authors demonstrated that use of image-guidance system seems to be beneficial for high cervical instrumentation which requires much experience and steep learning curves. However, incidence of cortex violation does not disappear completely due to the close proximity to spinal canal and surrounding vessels.