ACACIA AURICULIFORMIS-EXTRACT SYNTHESIS PR-PROTEINS DEVELOPED POTENTIAL BIOMEDICINES-VACCINE AGAINST OKRA-DISEASES AND COVID-19: IMPROVED SCIENCE TECHNOLOGY COMMUNICATIONS BIO-ECONOMY APPLICATIONS

Subhas Chandra Datta

doi:10.29121/granthaalayah.v8.i10.2020.1893

Abstract

The pandemic COVID19, effects on global health, educations, clinical research, human civilization, and the economy. So, it has been an urgency to develop proper vaccines against coronavirus. India emphasis on the most nutritious economically-important number-one-consumption-vegetable, okra, used in many human diseases, is naturally infected by different pathogens and significantly reduces production. Though pesticides are the most effective means of control, but they are expensive and toxic to the environment. So, it will require new and more efficient solutions, technologies, products, and methods. Present pre- and post-treatment with biomedicines; Acacia auriculiformis-extract, prepared from the funicles of Acacia auriculiformis A. Cunn., dissolved in sterile tap water at 1mg/10ml, were applied by foliar spray once daily for 15 days @ 10 ml/plant, against Root-Knot (RK), Yellow Vein Mosaic Virus (YVMV) and Okra Enation Leaf Curl Virus (OELCV) diseases of okra, (Abelmoschus esculentus L. Moench) cv.Ankur-40. The soluble root-proteins were separated by using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and were scanned with a recording densitometer electrophoretic scanner, measuring the molecular weight of proteins. Pre- and post-treatment with high-diluted-biomedicines; Acacia auriculiformis extract, were highly effective in reducing different okra-diseases by synthesis of new pathogenesis-related-protein (PR-proteins), inducing their natural defense-response against pathogens-infection and enhanced their growth as well as protein content of fruits and roots. The high-diluted-biomedicines; Acacia auriculiformis extract, not only used as a potential-biomedical-drugs or vaccine against various plant-diseases, by synthesis of new PR-proteins, increasing natural-defense-response, but also, it may help for the preparation of a vaccine against COVID-19, by increasing immunity and enriching science and technology communications applications, cost-effectiveness and biodiversity conservations as well as bio-economy-applications issues, reviving human civilizations in the old form. And in near future okra may itself be a ‘Potential Biomedicine as well as Vaccine’ and world will return in normal form by defeating COVID-19.

Highlights

The COVID19, pandemic problems [1], effects on our private, professional life, social life, and the socialorganization-communities [1], global health, travel, economy, and human civilization, as well as the clinical research, Acacia Auriculiformis-Extract Synthesis PR-Proteins Developed Potential Biomedicines-Vaccine Against Okra-Diseases and Covid-19: Improved Science Technology Communications Bio-Economy Applications with scientists, has been an urgency to develop vaccines against coronavirus [2] for the unusual viral pneumonia in patients and different animals [3], forming the fifth endemic coronavirus, leaping from animals to humans, becoming a health danger [4]
To meet the challenge of the pandemic problems, India emphasis on the most economically important number one consumption-vegetable crop [11], okra, used as traditional medicine, the ‘Nature's Gift to human disease-free healthy life’ [12], consumed in a variety of ways, fruits rich in vitamins, calcium, folic acid, carbohydrates, phosphorus, magnesium, and potassium [13], iodine, and other mineral matters, and a good source of superior nutritional quality -oil and –protein, unsaturated fatty acids such as linoleic acid, which is essential for human nutrition, and mature fruit and stems contain crude fiber, used in the paper industry, and the mucilage of roots- and stems- is used in the sugarcane industry of India achieved first in the world [13]
In India, the production in terms of yield as well as fruit quality of okra is hampered adversely by the naturally occurring Root-Knot (RK) diseases caused by the nematode-pathogens, Meloidogyne incognita (Kofoid and white, Chitwood, 1949), Yellow Vein Mosaic Virus (YVMV) disease- and Okra Enation Leaf Curl Virus (OELCV) disease, caused by the virus-pathogens which spreads by an insect vector, named-whitefly (Bemisia tabaci Gen)

Summary

Introduction

The COVID19, pandemic problems [1], effects on our private, professional life, social life, and the socialorganization-communities [1], global health, travel, economy, and human civilization, as well as the clinical research, Acacia Auriculiformis-Extract Synthesis PR-Proteins Developed Potential Biomedicines-Vaccine Against Okra-Diseases and Covid-19: Improved Science Technology Communications Bio-Economy Applications with scientists, has been an urgency to develop vaccines against coronavirus [2] for the unusual viral pneumonia in patients and different animals [3], forming the fifth endemic coronavirus, leaping from animals to humans, becoming a health danger [4]. A number of plant –bioagents [19], [20], [21] or –bio-nematicides [15], [22], [23] and intercropping [24], [25], [26], [27], and biomedicine [28], [29], [30], [31] only stand as a suitable- and useful- against different plants-, animals- and human- diseases caused by pathogens It remains some problems [32], [33], [34], [35]. To meet the challenge of the problems; it is already reported that the Biomedicines; Aakashmoni or Acaciasides (A&B) or Acacia auriculiformis extract, is being used traditionally to overcome various medical complications [14], [15], [19], [20], [21], [22], [28], [29], [30], [31], [33], due to presence of several medical ailments and effective bioactive phytoconstituents, and to its low toxicity and high efficacy [34], [35]

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