Abstract
Introduction: Tools for evaluating risk of post-intervention risk hemorrhage in the setting of acute stroke include a noncontrast head CT based Alberta Stroke Program Early CT score (ASPECTS) and contrasted CT based perfusion plots. The correlation between these parameters is unknown. Methods: We performed a retrospective analysis of a prospectively collected endovascular stroke database of patients with M1 middle cerebral artery occlusion who underwent endovascular recanalization. We reviewed admission preintervention noncontrast CT for Alberta Stroke Program Early CT score (ASPECTS) and 320-detector row whole brain CT perfusion parameters (Cerebral blood volume and time to peak). Pearson correlation was determined between cerebral blood volume on the side of the stroke and ASPECTS. Results: ASPECTS and CT perfusion map were identified in 45 and 43 patients respectively. Statistically significant correlation was found between ASPECTS and cerebral blood volume data on CT perfusion MAP. (p=0.034, r=-0.28). The correlation coefficient is very weak. No correlation could be found between time to peak and ASPECTS. Conclusion: A statistically significant, but weak correlation exists between ASPECTS and CBV. Further research is needed to assess the physiological meaning of diverse imaging modalities utilized in the acute stroke setting.
Published Version
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