Abstract PD15-01: Impact of ESR1 mutations on endocrine therapy (ET) plus alpelisib benefit in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-), PIK3CA-mutated, advanced breast cancer (ABC) who progressed on or after prior cyclin-dependent kinase inhibitor (CDK4/6i) therapy in the BYLieve trial

Nick Turner,Murat Akdere,Hope S Rugo,Dejan Juric,Estelle Roux,Aleix Prat,Alejandro Balbin,Eva M Ciruelos,Pamela Drullinsky,Christina H Arce,Manuel Ruiz-Borrego,Mukta Joshi,Stephen Chia,Thomas Bachelot,Florence Lerebours

doi:10.1158/1538-7445.sabcs21-pd15-01

Abstract PD15-01: Impact of ESR1 mutations on endocrine therapy (ET) plus alpelisib benefit in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-), PIK3CA-mutated, advanced breast cancer (ABC) who progressed on or after prior cyclin-dependent kinase inhibitor (CDK4/6i) therapy in the BYLieve trial

Nick Turner, Murat Akdere + Show 13 more

https://doi.org/10.1158/1538-7445.sabcs21-pd15-01

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Journal: Cancer Research	Publication Date: Feb 15, 2022
Citations: 3

Affiliation: Novartis (Switzerland), University of California, San Francisco, Massachusetts General Hospital, Hospital Clínic de Barcelona, Boston Biomedical Research Institute, Hospital Universitario 12 De Octubre, Memorial Sloan Kettering Cancer Center, Tris Pharma (United States), BC Cancer Agency, University of British Columbia, Centre Léon Bérard, Institute Curie

#Alpelisib #Prior Therapy + Show 8 more

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Abstract PD15-01: Impact of <i>ESR1</i> mutations on endocrine therapy (ET) plus alpelisib benefit in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-), <i>PIK3CA</i>-mutated, advanced breast cancer (ABC) who progressed on or after prior cyclin-dependent kinase inhibitor (CDK4/6i) therapy in the BYLieve trial

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