Abstract P-525: ELECTROENCEPHALOGRAPHY MONITORING AND ELECTROGRAPHIC SEIZURES IN PEDIATRIC INTENSIVE CARE UNIT PATIENTS

Abstract

Aims & Objectives: To study the EEG (electroencephalography) background and electrographic seizures in PICU (pediatric intensive care unit) patients who underwent bedside VEEG (video-EEG) monitoring, risk factors for electrographic seizures, and whether background and/or electrographic seizures were associated with increased in-hospital mortality. Methods Pediatric patients admitted or transferred to PICU who underwent VEEG monitoring were retrospectively enrolled. Data on demographics, diagnoses, clinical seizures, EEG background, electrographic seizures, length of PICU stay, and in-hospital mortality were also collected. Results During July 2013 and June 2016, 128 consecutive children (71 boys and 57 girls) in PICU underwent VEEG monitoring for 202 times. The median age was 1.4 years (from 26 days to 17.4 years). Electrographic seizures occurred in 42 patients (32.8%), of which 17 cases (40.5%) had electrographic status epilepticus. Severe abnormal EEG background was associated with electrographic seizures (P<0.001). Patients with electrographic status epilepticus had greater odds of in-hospital death. Conclusions Electrographic seizures are common among children in the PICU. Electrographic status epilepticus occurs in more than one-third of children with electrographic seizures and is associated with higher in-hospital mortality.