Abstract P4-01-12: Compliance with Recommended Follow-Up after MRI-guided Core Needle Biopsy of Suspicious Breast Lesions: A Retrospective Study

Abstract

Abstract Purpose: The purpose of this study was to assess patient compliance with recommended follow-up after MRI-guided core needle biopsy and investigate the reasons why patients did not comply with their recommended MRI imaging follow-up. Materials and Methods: A HIPAA compliant retrospective review was performed of 576 MRI-guided core needle biopsies between 2007–2010 with IRB approval and waiver of informed consent. Of 576 biopsies, 73.3% (422/576) were compliant and 26.7% (154/576) were noncompliant with follow-up recommendations and composed this study. Imaging and surgical planning was determined by comparing imaging findings, clinical findings, and biopsy histology. Results: Out of 135 lesions in patients noncompliant with follow-up imaging, 50.4% (68/135) were referred for biopsy by non-affiliated physicians, 41.5% (56/135) received a screening MRI, and 40.3% (56/135) were a focus or foci. Referring physicians provided information regarding the follow-up status of 88/154 (57%) lesions in noncompliant patients, of which 44/88 (50%) were followed by mammogram instead of MRI. Among compliant patients, 7/178 (3.9%) lesions seen on follow-up MRI were found to be high risk or malignant. Conclusion: Compliance with follow-up MRI recommendation after core needle biopsy is low. Three characteristics were found to be associated with noncompliance with follow-up imaging: referral from non-affiliated physician, screening MRI, and a focus lesion. Moreover, patients who do not comply with recommended MRI follow-up are more likely to have follow-up mammography. Follow-up imaging among compliant patients found high-risk lesions and malignancy. Facilities performing MRI-guided core biopsies should therefore be aware of a high risk of noncompliance with follow-up. Citation Information: Cancer Res 2012;72(24 Suppl):Abstract nr P4-01-12.