Abstract P-509: THE VALUE OF MONITORING BRAIN OXYGEN SATURATION IN CHILDREN SEPSIS WITH NEAR INFRARED SPECTROSCOPY

Abstract

Aims & Objectives: To examine the difference of rScO2 in children with sepsis via NIRS Methods We monitored the rScO2 of sepsis children. We tried to find the change rule of rScO2 and explore the relationship between rScO2 and some physiological indicators. And then we studied the relationship between rScO2 and prognosis Results A total of 30 subjects were enrolled into this study, which included 17 septic shock children and 13 non-shock children. The rScO2 of septic shock children is significantly lower than the non-shock children and the control group in the first 4–5 day after admission (58.8% vs 63.5%). There is no statistically difference between non-shock group and the control group in rScO2. The rScO2 is not statistically correlated with mean arterial pressure, heart rate, and the concentration of hemoglobin and lactic acid, but has a positive relationship with ScvO2, the correlation coefficient is about 0.6–0.7. Although there is no statistically significant correlation between rScO2 and GOS, the rScO2 in dead children is lower than that of surviving children (57.6% vs 62.8%) Conclusions The rScO2 has strong positive correlation with ScvO2. Compared with survivors, the rScO2 is lower in dead children. NIRS may be a predictive factor in children sepsis