Abstract
Abstract Prostate cancer is a public health concern among 50 year old the men worldwide and its incidence keep rising. It is triggered by genome instability or epigenetic modifications impacting DNA repair and tumor suppression genes and proteins. In African countries, little data is available on prostate cancer and the loss of BRCA1 exons responsible for tumor suppression. It is in this context that we undertook this study, the general objective of which is to assess the association between BRCA1 instability in patients with prostate cancer, These men with prostate cancer usually present with symptoms like nocturia and poor urinary flow, erectile dysfunction and visible hematuria. Citation Format: Haboubacar Elhadji Yaou Moussa, Callinis Capo Chichi. Prostate cancer prevention is possible thanks to the evaluation of the primary exons of the BRCA1 biomarker in men [abstract]. In: Proceedings of the AACR Special Conference: Advances in Prostate Cancer Research; 2023 Mar 15-18; Denver, Colorado. Philadelphia (PA): AACR; Cancer Res 2023;83(11 Suppl):Abstract nr B052.
Published Version
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