Abstract A51: Ethnic and gender disparities in limb-salvage rates among pediatric sarcoma patients

Abstract

Abstract Introduction: Racial and ethnic disparities in limb-salvage surgery have been reported among adult sarcoma patients. The purpose of this work was to explore treatment patterns by ethnicity and gender in a cohort of pediatric sarcoma patients Methods: A retrospective review was conducted of all consecutive patients under the age of 18 treated for sarcoma at the study institution with diagnoses from 1999 to 2011 who underwent surgery for limb salvage or amputation. Statistical analysis of patient demographics (age, sex, ethnicity and BMI) was performed to assess for factors associated with limb salvage surgery. Results: 51 records were identified as pediatric patients who underwent surgery for extremity sarcoma in the defined study period. 5 records were excluded due to inadequate availability of body site or surgery type documentation, leaving a cohort of 46 patients. Hispanic patients were more likely to undergo amputation (10 of 36) compared to non-Hispanics (5 of 10; p = 0.03). Female patients were more likely to have had limb salvage (8 of 17) than males (7 of 29; p = 0.04). Logistic regression analysis showed no difference between likelihood of limb salvage and amputation when stratified by BMI or age. Conclusions: Hispanic ethnicity and male gender were predictors of amputation in a cohort of pediatric sarcoma patients undergoing surgical treatment. Further study should be devoted to identifying underlying factors for ethnic and gender discrepancies between treatment groups. Citation Format: Jeremy Somerson, Isaac Kim, Rajiv Rajani. Ethnic and gender disparities in limb-salvage rates among pediatric sarcoma patients. [abstract]. In: Proceedings of the Seventh AACR Conference on The Science of Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; Nov 9-12, 2014; San Antonio, TX. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2015;24(10 Suppl):Abstract nr A51.