Abstract 624: Racial Difference In Acute Myocardial Infarction-Mortality During Covid-19

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Introduction: Covid-19 pandemic had detrimental effects on the healthcare system. studies have shown a significant increase in Acute Myocardial Infarction (AMI) mortality across different age and gender groups. Hypothesis: We assessed the hypothesis that the covid-19 pandemic had a significant negative impact on AMI mortality based on race. Methods: We queried January 2019 to December 2020 National Inpatient Sample (NIS) database to identify AMI hospitalizations in adults (>18 years old). AMI mortality was then identified in each racial group (White, Black, and Hispanic). Multivariate logistic regression was used in outcomes analysis to adjust for potential patient-related and hospital-level confounders (age, sex, diabetes, heart failure, chronic kidney disease, Charlson Comorbidity Index score, hospital location, income status, and others), ICD-10-CM codes were utilized to identify the above-listed comorbidities. Results: 743,429 AMI hospitalizations were identified during the period of interest. Of these 72.1% were White, 11.9% were Black, and 9.3% were Hispanic, with 38.1% of all patients being females. The mean age was 69 in Whites, 63.5 in Blacks, and 65.2 in Hispanics (p<0.01). After adjusting for potential confounders, analysis results showed significantly higher odds of AMI mortality in Blacks and Hispanics as compared to Whites (aOR 1.10 (1.03-1.14); p = 0.01) and (aOR 1.22 (1.14-1.31); p < 0.01) respectively in the period between January 2020 to December 2020 (Figure 1). This contrasts to similar odds of AMI mortality across the different races (Black vs. White aOR 0.95 (0.89-1.02); p = 0.22) and (Hispanic vs. White aOR 1.01 (0.94-1.09); p = 0.62) seen in the year preceding the pandemic (January 2019-December 2019). Conclusion: Our analysis demonstrates increased odds of AMI mortality in Blacks and Hispanics compared to Whites in the period between January 2020-December 2020 when compared to the pre-pandemic period (January 2019-December 2019).