Abstract 16767: Utilization Trends and Sex Disparities in Cardiac Magnetic Resonance Imaging for Cardiovascular Diseases: Insights From TriNetX, a Large Database Analysis

Abstract

Introduction: Cardiac magnetic resonance imaging (CMR) is an important imaging modality for diagnosing cardiovascular diseases and optimizing therapeutic management. We assessed CMR utilization and potential sex disparities for myocarditis, Takotsubo cardiomyopathy (CM), heart failure, and amyloidosis. Methods: Using the TriNetX database, we conducted a comprehensive analysis, querying adults with diagnoses of these four diseases. CMR risk within 1 year of ICD-10 diagnosis was assessed. Trends in CMR incidence proportion and prevalence between 2015 and 2022 were examined. Odds ratios were used to assess the presence of both sex disparities and temporal differences in CMR utilization for myocarditis in the COVID-19 era. Results: Overall increasing prevalence and incidence proportion of CMR for these four diagnoses are presented in Figure 1. CMR utilization for patients with myocarditis (10.4%), remained consistent between 2019 and 2020. However, the odds of CMR slightly increased in 2021 and then declined in 2022. CMR utilization for Takotsubo, heart failure, and amyloidosis diagnoses was lower, 2.4%, 1.3%, and 4.4%, respectively. Odds ratios revealed higher likelihood of CMR ordered for males than females diagnosed with Takotsubo CM [OR 1.352* (1.143, 1.599)], heart failure [ OR 1.248* (1.221,1.277)], and amyloidosis [OR 1.375* (1.261,1.499)]. Conclusions: Despite CMR's diagnostic and prognostic utility in patients with suspected myocarditis, heart failure, Takotsubo CM, and amyloidosis, CMR utilization is rising but low, with significant sex disparities in referral patterns. Further studies are needed to determine how increased CMR utilization impacts cardiovascular disease diagnosis, patient outcomes, and sex disparities.