Abstract 16706: Chronic Kidney Disease Among U.S.-Born and Foreign-Born U.S. Adults in the 2011-2018 National Health and Nutrition Examination Survey

Abstract

Introduction: Chronic Kidney Disease (CKD) is a major risk factor for cardiovascular disease (CVD) and death. Hispanic and African American persons have poorer control of CVD risk factors and are disproportionately affected by CKD, CVD, and their associated complications compared to White persons. Objective: To compare the prevalence of CKD and Reduced Kidney Function (RKF) by nativity status in the U.S. Methods: Using pooled 2011-2018 National Health and Nutrition Examination Survey (NHANES) data, we examined the prevalence of CKD in a weighted sample of U.S.- and foreign-born adults. RKF was defined as eGFR <60mL/minute/1.73m 2 (CKD-EPI equation), and CKD was defined as eGFR <60mL/minute/1.73m 2 and an albumin-creatinine ratio ≥30 mg/g. We used multivariable Poisson models to estimate the association between CKD and nativity status, adjusting for covariates. Results: We included a sample of 39,143 adults; mean age was 46.8(±0.31) years, 52% female, and 18% were foreign-born. The prevalence of CKD among U.S.-born adults was 14.8%, compared to 11.8% of foreign-born adults. After adjusting for covariates, foreign-born adults were 21% less likely to have CKD (prevalence ratio: 0.79, 95%CI 0.67-0.91) and 29% less likely to have RKF (PR: 0.71, 95% CI 0.56-0.89) compared to U.S.-born ( Table ). Conclusions: Foreign-born persons were less likely to have CKD and RKF than U.S.-born adults. Public health efforts are needed to maintain this health advantage among foreign-born adults and to reduce the burden of CKD in the U.S.-born population.