Abstract 15193: The Impact of Age and Gender on Door to Balloon Time in Patients with ST Elevation Myocardial Infarction

Abstract

Introduction: Shortening door-to-balloon (D2B) time is important to improve outcomes in patients suffering ST elevated acute myocardial infarction (STEMI). Age and gender are associated with poor outcomes in previous reports, however the impact of differences in age and gender on D2B time is still unclear. Objective: To determine the association of age and gender with D2B time in patients suffering STEMI. Methods: The Yokohama cardiovascular workshop registry is a prospective multicenter cohort in an urban area of Japan. 1261 consecutive STEMI patients during May 2010 to May 2013 were enrolled for the present analysis. Patients were divided into four groups according to age (>75years old) and gender; elderly female (n=146), young female (n=125), elderly male (n=206) and young male (n=783). Results: D2B time was longer in female gender (93.2 vs. 85.5 min, p<0.01) and in the elderly (92.3 vs. 85.1, p<0.001). Among the four groups described above, D2B time was the longest in elderly female patients and followed by young female patients (p=0.002). Elderly female patients also had the lowest proportion of Killip class I, the longest time interval from hospital arrival to achieve TIMI flow grade 2/3, the worst final TIMI flow grade and the highest in-hospital mortality. The percentage of patients in achieving D2B time <90min was the lowest in elderly male (p<0.001, odds ratio 0.54) followed by elderly female (p=0.009, odds ratio 0.61). Conclusions: Both female gender and higher age were associated with longer D2B time in patients with STEMI. Further effort should be made to shorten the D2B time, especially in the elderly and women, for the improvement of clinical outcomes.