Abstract

Background: Atrial fibrillation (AF) is a prevalent cardiovascular disease in the elderly population. Restoring sinus rhythm in AF often involves antiarrhythmic drugs, direct current (DC) cardioversion, and ablation. The predictive value of left atrial appendage (LAA) emptying velocity in determining the energy required for successful DC cardioversion remains uncertain. Aim: To study the association between LAA emptying velocity and the amount of energy required for cardioversion in patients with AF undergoing DC cardioversion. Methods: A total of 79 consecutive AF patients were enrolled in the study. Transesophageal echocardiography was performed to exclude the presence of clot formation, after which patients underwent DC cardioversion using escalating biphasic energy levels of 100 joules, 200 joules, and 360 joules to restore sinus rhythm. Patients were stratified into two groups based on LAA emptying velocity: the low-velocity group (≤30 cm/sec) and the high-velocity group (>30 cm/sec). Clinical characteristics were compared between the groups. Results: Of the 79 patients, 49 had a low LAA emptying velocity (LAAEV). The low-velocity group was older, with a mean age of 75 years compared to 70 years in the high-velocity group. The severity of mitral regurgitation was similar between the two groups. Patients with reduced LAA emptying velocity required significantly higher joules for successful cardioversion compared to the high-velocity group (192 joules vs. 155 joules, p-value = 0.02). Sleep apnea was more prevalent in the high-velocity group. The utilization of antiarrhythmic medications did not differ significantly between the groups (55% vs. 63%, p-value = 0.25). Conclusions: The study showed AF patients with low LAA emptying velocity require higher energy levels for successful cardioversion, suggesting that LAA emptying velocity may serve as a predictor of energy requirement in DC cardioversion for restoring sinus rhythm in AF patients.

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