Abstract 10088: Atrial Fibrillation/Atrial Flutter Related Mortality Rates Among the Young Population; Data from CDC Wonder 1999-2019

Abstract

Introduction: Atrial fibrillation (AF) majorly effects the elderly, but it can also affect the younger population. The aim of this study was to examine the trends in AF related deaths in the young population in the United States from 1999 to 2019. Methods: We used CDC Wide-ranging Online Data for Epidemiologic Research (CDC WONDER) to access National Vital Statistics System data from 1999 to 2019. AF associated deaths, age 15- 44 years were identified from multiple causes of death and were represented as age-adjusted mortality rates (AAMR) per 1,000,000 population. Joinpoint regression was used to examine changes in trend and annual percentage change (APC) overall and stratified by sex and racial/ethnic groups. Results: AAMR related to AF decreased from 1.3 in 1999 to 3.7 in 2019 (APC 5.4 [95% CI, 4.8 to 6.0]). AAMR was higher in men (3.1) than women (1.3). AAMR was highest in blacks (4.4) followed by whites (1.9) and others (1.5) (includes Asian or Pacific Islanders; and American Indian or Alaska Natives). AAMR was highest in Black males (6.4). APC in AAMR increased in men (5.4) during the entire study period. In women, APC increased till 2010 (2.5) and then further accelerated till 2019 (8.4). APC in AAMR increased in Whites (5.6) and Blacks (5.3) during the entire study period. Conclusion: AF associated mortality has been consistently increasing in the younger population across all sexes and races. Further research is needed to understand the underlying factors to help develop preventative strategies.