Abstract
ABO Blood Groups and Hyperbaric Oxygen Therapy Effectiveness in Sudden Hearing Loss
Highlights
Human ABO blood type is determined by a gene on chromosome 9.ABO blood group is the first genetic polymorphism recognized in humans [1]
The distributions of blood group antigens of all idiopathic sudden sensorineural hearing loss (ISSNHL) patients are given in Table 1.While the majority of patients had O (n: 154) blood type, ISSNHL patients with AB blood group had a statistically higher smoking percentage than other blood group patients
Serum uric acid (UA) level was statistically higher in patients with blood type A, but UA and fasting blood glucose (FBG) levels were within normal limits in all blood groups (Table 1)
Summary
Human ABO blood type is determined by a gene on chromosome 9.ABO blood group is the first genetic polymorphism recognized in humans [1]. It has been reported that ISSNHL is associated with many vascular and coagulation diseases [35] Dyslipidemia is one of the most important cardiovascular risk factors, which is defined as a cardiovascular risk factor in European societies and evidence has shown that there is a relationship between ISSNHL and dyslipidemia [6, 7] These findings led to the hypothesis that non-O blood group antigens may have higher levels of dyslipidemia and an inflammatory condition and oxidative stress may occur [3,4,5]. The contribution of ABO blood group distribution to the response efficiency of HBO therapy in ISSNHL patients is unknown The aim of this preliminary study is to evaluate the possible effect of the distribution of new atherogenic risk indices by blood groups in ISSNHL patients on HBO therapy
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